INN monograph
Iron III hydroxide sucrose complex injection
Vitamin / mineral / nutritional supplement · POM
Verified · Updated 01 Aug 2026 · Source: Local active-ingredient clinical extract; Professional class pharmacology (Vitamin / mineral / nutritional supplement)
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
- Hypervitaminosis risk states (hypercalcaemia for vitamin D/A).
- Iron: avoid in iron overload.
- Potassium: severe hyperkalaemia / untreated Addison's.
Precautions
- Treat confirmed deficiency with monitored repletion.
- Avoid megadoses without indication.
- Iron: keep away from children (overdose lethal).
Point of care
Dosing
Adult
The dose depends on the hemoglobin level: IV infusion or slow injection, 100mg iron 1 to 3 times per week (the maximum treatment regimen is 1,000 mg in 10 doses).
Paediatric
See label paediatric section if present; otherwise use paediatric formulary — do not extrapolate adult doses.
Renal
Fat-soluble vitamins and potassium need care in advanced CKD.
- CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Hepatic
Vitamin A toxicity hepatic; niacin hepatotoxicity at high dose.
Safety
Drug interactions
- Prefer food-first then targeted replacement.
- Document laboratory indication for high-dose therapy.
- Public health: vitamin A, iron, folate programmes per MoH guidance.
Safety
Adverse effects
- GI upset (iron, high-dose vitamin C).
- Hypercalcaemia (vitamin D excess).
- Neuropathy with B6 megadoses.
- Flushing (niacin).
Use
Indications
- Iron deficiency anemia in chronic hemodialysis and patients on supplemental erythropoietin therapy, Iron deficiency before and after surgery, final stages of pregnancy, intolerance, non-responsiveness or non-compliance to oral iron therapy,
- malabsorption etc.
Pharmacology
Mode of action
Iron is an important component of hemoglobin and myoglobin that are responsible for oxygen transport within the body.
Full mechanism text
Iron is an important component of hemoglobin and myoglobin that are responsible for oxygen transport within the body. It also serves as a cofactor of several essential enzymes like cytochromes that are involved in electron transport. It is essential for catecholamine metabolism and the proper functioning of neutrophils.
ADME
Pharmacokinetics & PD
| Onset | Days–weeks for repletion |
|---|---|
| Duration | Depends on stores and ongoing intake |
| Route | ORAL / IM / IV (selected) |
| Absorption | depends on GI integrity, food matrix and binders (e.g. calcium/iron interactions). Fat-soluble vitamins (A,D,E,K) accumulate; water-soluble generally renally cleared. |
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| Feromax | Gulf Pharmaceuticals (See also Julphar) | Standard Commercial Pack | — |
| Ferracin | Acino International AG | Standard Commercial Pack | — |
| Ferrasil | Arwan Pharmaceutical Industries | Standard Commercial Pack | — |
| Ferrose | Distributed by Galaxy | Standard Commercial Pack | — |
| Hembrans | Brawn Laboratories Ltd | Standard Commercial Pack | — |
| Hemofer | Popular Pharmaceuticals Ltd | Standard Commercial Pack | — |
| Megafer | Nabiqasim Industries (Pvt) Ltd | Standard Commercial Pack | — |
Special populations
Pregnancy & lactation
Pregnancy
Folic acid preconception/first trimester critical. Iron/folate common in ANC. Avoid excess vitamin A.
Lactation
Maternal repletion often appropriate; avoid megadoses.
Diet
Food & alcohol
- Food
- Food
Trust
Sources & disclaimer
Source: Local active-ingredient clinical extract; Professional class pharmacology (Vitamin / mineral / nutritional supplement)
Last reviewed: 01 Aug 2026
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.