INN monograph
Azithromycin Dihydrate
Macrolides · POM
Verified · Updated 23 Jul 2026
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
No structured CI text — verify product SmPC.
Point of care
Dosing
Adult
See SmPC / STG for indication-specific dose.
Paediatric
Weight-based — use paediatric formulary / SmPC.
Renal
Check SmPC; many renally cleared drugs need CrCl adjustment.
Hepatic
Check SmPC in significant liver disease.
Safety
Drug interactions
No structured interaction monograph text. Use the multi-drug checker and SmPC.
Safety
Adverse effects
ADR text pending — consult SmPC.
Use
Indications
PPB Registered Human Medicine.
Pharmacology
Mode of action
Macrolide: binds the 50S ribosomal subunit and inhibits bacterial protein synthesis (usually bacteriostatic; may be bactericidal at high concentrations against highly susceptible organisms).
Full mechanism text
Macrolide: binds the 50S ribosomal subunit and inhibits bacterial protein synthesis (usually bacteriostatic; may be bactericidal at high concentrations against highly susceptible organisms).
ADME
Pharmacokinetics & PD
| Route | ORAL |
|---|
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| Agycin | Elys Chemical Industries Ltd | Film-Coated Tablet (36 months) | 1,477.00 |
| Agycin 500mg | Alembic Pharmaceuticals Ltd | Film-Coated Tablet (36 months) | 446.00 |
| Azifast | Alembic Pharmaceuticals Ltd | Film-Coated Tablet (36 months) | 946.00 |
| Azifast 500mg | MACLEODS PHARMACEUTICALS LTD | Film-Coated Tablet (36 months) | 282.00 |
| Azimax | SUN PHARMA KENYA LTD | Film-Coated Tablet (36 months) | 1,134.00 |
| Azimax 500mg | Biodeal Laboratories Ltd | Film-Coated Tablet (36 months) | 305.00 |
| Zithromax | SUN PHARMA KENYA LTD | Film-Coated Tablet (36 months) | 975.00 |
| Zithromax 500mg | HARLEYS LIMITED | Film-Coated Tablet (36 months) | 473.00 |
| Zithrox | Regal Pharmaceuticals Ltd | Film-Coated Tablet (36 months) | 1,391.00 |
| Zithrox 500mg | Regal Pharmaceuticals Ltd | Film-Coated Tablet (36 months) | 613.00 |
Special populations
Pregnancy & lactation
Pregnancy
See SmPC / obstetric guidance.
Lactation
See SmPC / lactation reference.
Diet
Food & alcohol
- Grapefruit & Grapefruit Juice Inhibits intestinal CYP3A4 metabolism of macrolides (e.g. Clarithromycin, Erythromycin), increasing serum concentrations and risk of QTc prolongation and ototoxicity.
Trust
Sources & disclaimer
Source: MyDrugIndex clinical corpus
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.