INN monograph
Amoxicillin trihydrate and Potassium Clavulanate
J01CR02 · POM
Verified · Updated 23 Jul 2026
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
No structured CI text — verify product SmPC.
Point of care
Dosing
Adult
See SmPC / STG for indication-specific dose.
Paediatric
Weight-based — use paediatric formulary / SmPC.
Renal
Check SmPC; many renally cleared drugs need CrCl adjustment.
Hepatic
Check SmPC in significant liver disease.
Safety
Drug interactions
No structured interaction monograph text. Use the multi-drug checker and SmPC.
Safety
Adverse effects
ADR text pending — consult SmPC.
Use
Indications
PPB Registered Human Medicine.
Pharmacology
Mode of action
Amoxicillin inhibits bacterial cell-wall synthesis by binding penicillin-binding proteins (PBPs).
Full mechanism text
Amoxicillin inhibits bacterial cell-wall synthesis by binding penicillin-binding proteins (PBPs). Clavulanic acid is a beta-lactamase inhibitor that protects amoxicillin from enzymatic hydrolysis. Combined effect: bactericidal activity against many beta-lactamase–producing organisms that would otherwise resist amoxicillin alone.
ADME
Pharmacokinetics & PD
| Route | Dispersible Tablet |
|---|
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| Nelclav-DT | info@chirospharma.com | H2021/CTD8628/16938 (36 months) | 460.00 |
Special populations
Pregnancy & lactation
Pregnancy
See SmPC / obstetric guidance.
Lactation
See SmPC / lactation reference.
Diet
Food & alcohol
- Food & Meals Food reduces gastric acid stability and oral absorption of plain penicillins (e.g. Ampicillin, Penicillin V). Take 1 hour before or 2 hours after meals with a full glass of water.
Trust
Sources & disclaimer
Source: MyDrugIndex clinical corpus
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.