INN monograph
Amikacin sulphate USP equivalent to amikacin
Aminoglycosides · POM
Verified · Updated 23 Jul 2026
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
No structured CI text — verify product SmPC.
Point of care
Dosing
Adult
See SmPC / STG for indication-specific dose.
Paediatric
Weight-based — use paediatric formulary / SmPC.
Renal
Check SmPC; many renally cleared drugs need CrCl adjustment.
Hepatic
Check SmPC in significant liver disease.
Safety
Drug interactions
No structured interaction monograph text. Use the multi-drug checker and SmPC.
Safety
Adverse effects
ADR text pending — consult SmPC.
Use
Indications
PPB Registered Human Medicine.
Pharmacology
Mode of action
Aminoglycoside: irreversibly binds the 30S ribosomal subunit, causing misreading of mRNA and inhibition of protein synthesis — concentration-dependent bactericidal activity, especially against Gram-negative aerobes.
Full mechanism text
Aminoglycoside: irreversibly binds the 30S ribosomal subunit, causing misreading of mRNA and inhibition of protein synthesis — concentration-dependent bactericidal activity, especially against Gram-negative aerobes.
ADME
Pharmacokinetics & PD
| Route | Makcur Laboratories Limited |
|---|
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| Makcin 100mg | — | Antibacterials for systemic use: Aminoglycosides (36 months) | 852.00 |
Special populations
Pregnancy & lactation
Pregnancy
See SmPC / obstetric guidance.
Lactation
See SmPC / lactation reference.
Diet
Food & alcohol
- Alcohol (Beer, Wine, Spirits) Avoid or limit alcohol consumption while taking Amikacin sulphate USP equivalent to amikacin. Alcohol may alter drug metabolism, enhance drowsiness, or exacerbate gastrointestinal irritation.
- Dietary Hydration & Meals Take Amikacin sulphate USP equivalent to amikacin with a full glass of water. If gastrointestinal upset occurs, take with or after light meals.
Trust
Sources & disclaimer
Source: MyDrugIndex clinical corpus
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.