INN monograph
Paracetamol BP, Aspirin BP, Caffeine BP
paracetamol · POM
Verified · Updated 23 Jul 2026
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
No structured CI text — verify product SmPC.
Point of care
Dosing
Adult
See SmPC / STG for indication-specific dose.
Paediatric
Weight-based — use paediatric formulary / SmPC.
Renal
Check SmPC; many renally cleared drugs need CrCl adjustment.
Hepatic
Check SmPC in significant liver disease.
Safety
Drug interactions
No structured interaction monograph text. Use the multi-drug checker and SmPC.
Safety
Adverse effects
ADR text pending — consult SmPC.
Use
Indications
PPB Registered Human Medicine.
Pharmacology
Mode of action
Central cyclo-oxygenase inhibition and serotonergic pathway effects produce analgesia and antipyresis with minimal peripheral anti-inflammatory action.
Full mechanism text
Central cyclo-oxygenase inhibition and serotonergic pathway effects produce analgesia and antipyresis with minimal peripheral anti-inflammatory action.
ADME
Pharmacokinetics & PD
| Route | Tablet |
|---|
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| PHARMADEX | SKYBIOTECH LIFE SCIENCES (P) LTD | H2021/CTD8341/16528 (36 months) | 798.00 |
Special populations
Pregnancy & lactation
Pregnancy
See SmPC / obstetric guidance.
Lactation
See SmPC / lactation reference.
Diet
Food & alcohol
- Chronic Heavy Alcohol Use Chronic alcohol intake induces CYP2E1 enzymes, accelerating formation of hepatotoxic metabolite (NAPQI) and increasing acute liver necrosis risk even at standard doses.
Trust
Sources & disclaimer
Source: MyDrugIndex clinical corpus
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.