INN monograph
Glimepride and Metformin
glimepiride · POM
Verified · Updated 23 Jul 2026
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
No structured CI text — verify product SmPC.
Point of care
Dosing
Adult
See SmPC / STG for indication-specific dose.
Paediatric
Weight-based — use paediatric formulary / SmPC.
Renal
Check SmPC; many renally cleared drugs need CrCl adjustment.
Hepatic
Check SmPC in significant liver disease.
Safety
Drug interactions
No structured interaction monograph text. Use the multi-drug checker and SmPC.
Safety
Adverse effects
ADR text pending — consult SmPC.
Use
Indications
PPB Registered Human Medicine.
Pharmacology
Mode of action
Mechanism not yet curated for this INN — confirm SmPC.
ADME
Pharmacokinetics & PD
| Route | Tablet |
|---|
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| Orinase-met 2.0 tablet | CCL PHARMA (PVT) LTD | H2018/CTD3045/696ER (36 months) | 232.00 |
Special populations
Pregnancy & lactation
Pregnancy
See SmPC / obstetric guidance.
Lactation
See SmPC / lactation reference.
Diet
Food & alcohol
- Alcohol Alcohol potentiates Metformin effect on hepatic lactate clearance, significantly raising the risk of fatal Lactic Acidosis and severe hypoglycemia.
- Food Intake (Meals) Always take Metformin with or immediately after meals to buffer gastrointestinal irritation, bloating, metallic taste, and diarrhea.
Trust
Sources & disclaimer
Source: MyDrugIndex clinical corpus
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.