INN monograph
Ampicillin Trihydrate BP
J01CA01 · POM
Verified · Updated 23 Jul 2026
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
No structured CI text — verify product SmPC.
Point of care
Dosing
Adult
See SmPC / STG for indication-specific dose.
Paediatric
Weight-based — use paediatric formulary / SmPC.
Renal
Check SmPC; many renally cleared drugs need CrCl adjustment.
Hepatic
Check SmPC in significant liver disease.
Safety
Drug interactions
No structured interaction monograph text. Use the multi-drug checker and SmPC.
Safety
Adverse effects
ADR text pending — consult SmPC.
Use
Indications
PPB Registered Human Medicine.
Pharmacology
Mode of action
Beta-lactam antibiotic: binds penicillin-binding proteins (PBPs), blocks peptidoglycan cross-linking, weakens the bacterial cell wall and causes bactericidal lysis of susceptible organisms.
Full mechanism text
Beta-lactam antibiotic: binds penicillin-binding proteins (PBPs), blocks peptidoglycan cross-linking, weakens the bacterial cell wall and causes bactericidal lysis of susceptible organisms.
ADME
Pharmacokinetics & PD
| Route | Capsule |
|---|
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| SANCILLIN 500 CAPSULES | info@sanjeevanibiotech.com | H2020/CTD5777/1510ER (36 months) | 975.00 |
Special populations
Pregnancy & lactation
Pregnancy
See SmPC / obstetric guidance.
Lactation
See SmPC / lactation reference.
Diet
Food & alcohol
- Food & Meals Food reduces gastric acid stability and oral absorption of plain penicillins (e.g. Ampicillin, Penicillin V). Take 1 hour before or 2 hours after meals with a full glass of water.
Trust
Sources & disclaimer
Source: MyDrugIndex clinical corpus
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.