INN monograph
Silymarin 70mg, Vit. B1 4mg, Vit B2 4mg, Vit B6 4mg, Vit B12 1.2mcg Nicotinamide 4mg, Calcium Pantothenate 8mg
Vitamins, Minerals & Nutrition · POM
Verified
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
No structured CI text — verify product SmPC.
Point of care
Dosing
Adult
1 cap TID then 1-2 cap OD (with food).
Paediatric
Weight-based — use paediatric formulary / SmPC.
Renal
Check SmPC; many renally cleared drugs need CrCl adjustment.
Hepatic
Check SmPC in significant liver disease.
Safety
Drug interactions
No structured interaction monograph text. Use the multi-drug checker and SmPC.
Safety
Adverse effects
- Slight diarrhea.
Use
Indications
Product label claim: Treatment of toxic and inflammatory liver disorders, and as an adjuvant in chronic liver disease
Pharmacology
Mode of action
Mechanism not yet curated for this INN — confirm SmPC.
ADME
Pharmacokinetics & PD
| Clinical PK/PD | Data pending. |
|---|
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| Simepar | Acino International AG | Standard Commercial Pack | — |
Special populations
Pregnancy & lactation
Pregnancy
See SmPC / obstetric guidance.
Lactation
See SmPC / lactation reference.
Diet
Food & alcohol
- Alcohol (Beer, Wine, Spirits) Avoid or limit alcohol consumption while taking Silymarin 70mg, Vit. B1 4mg, Vit B2 4mg, Vit B6 4mg, Vit B12 1.2mcg Nicotinamide 4mg, Calcium Pantothenate 8mg. Alcohol may alter drug metabolism, enhance drowsiness, or exacerbate gastrointestinal irritation.
- Dietary Hydration & Meals Take Silymarin 70mg, Vit. B1 4mg, Vit B2 4mg, Vit B6 4mg, Vit B12 1.2mcg Nicotinamide 4mg, Calcium Pantothenate 8mg with a full glass of water. If gastrointestinal upset occurs, take with or after light meals.
Trust
Sources & disclaimer
Source: MyDrugIndex clinical corpus
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.