INN monograph
Chondroitin sulphate/sodium hyaluronate
Therapeutic agent (verify pharmacological class) · POM
Verified · Updated 01 Aug 2026 · Source: Local active-ingredient clinical extract; Professional class pharmacology (Therapeutic agent (verify pharmacological class))
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
- [Chondroitin sulphate] Hypersensitivity to the active substance or excipients.
- Additional absolute contraindications are indication- and product-specific — consult SmPC.
Precautions
- Obtain allergy and medication history.
- Adjust for renal/hepatic impairment, pregnancy, lactation, extremes of age and interacting drugs.
- Use the lowest effective dose for the shortest appropriate duration.
- Monitor for expected class adverse effects.
Point of care
Dosing
Adult
Dosing is indication-, age-, weight- and organ-function-specific for this INN. Do not use class averages for high-risk patients. Confirm the exact regimen in the current SmPC and Kenya Standard Treatment Guidelines. Typical professional workflow: (1) confirm indication, (2) check renal/hepatic function, (3) screen interactions/allergies, (4) select dose/route/duration, (5) define monitoring.
Paediatric
Paediatric dosing is weight- and age-based; use a paediatric formulary / SmPC. Do not extrapolate adult tablets without calculation.
Renal
Review renal impairment dosing; many agents need CrCl/eGFR adjustment.
- CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Hepatic
Review hepatic impairment dosing; monitor LFTs if agent is hepatically cleared or hepatotoxic.
Safety
Drug interactions
- Professional use: confirm indication, dose, duration, monitoring and patient counselling points against current Kenya STG / EML and the product SmPC.
- Document allergy status and key interactions.
Safety
Adverse effects
- Adverse reactions vary by agent.
- Counsel on common predictable effects and serious warning symptoms (allergy, severe rash, jaundice, unusual bleeding, severe GI symptoms, neurological changes).
- Report suspected ADRs via national pharmacovigilance channels.
Use
Indications
- An eye surgical aid in cataract extraction and in intraocular lens implantation.
- Clinical selection for Chondroitin sulphate/sodium hyaluronate should follow culture results where relevant, Kenya STG/EML recommendations, and the current product SmPC.
- Class context: Therapeutic agent (verify pharmacological class).
- Confirm site-specific dose, duration and monitoring before prescribing.
Pharmacology
Mode of action
It is a viscoelastic preparation that preserves a deep anterior chamber in the course of anterior segment surgery thus lowering the probability of trauma to the corneal endothelium and adjacent ocular tissues.
Full mechanism text
It is a viscoelastic preparation that preserves a deep anterior chamber in the course of anterior segment surgery thus lowering the probability of trauma to the corneal endothelium and adjacent ocular tissues.
ADME
Pharmacokinetics & PD
| Onset | Product-specific |
|---|---|
| Duration | Product-specific |
| Route | See product SmPC |
| Elimination | are product-specific. Consider food effects, protein binding, hepatic CYP/UGT |
| Half-life | when adjusting for organ impairment, age and drug interactions. Verify parameters in the current SmPC. |
Full PK/PD text
Absorption, distribution, metabolism and excretion are product-specific. Consider food effects, protein binding, hepatic CYP/UGT metabolism, renal clearance and half-life when adjusting for organ impairment, age and drug interactions. Verify parameters in the current SmPC.
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| Cartil (Collagen 150mg Glucosamine sulphate Potassium Chloride 500mg, Chondroitin sulphate sodium 100, Vitamin C 30mg, Cissus quadrangularis extract 300mg, Hyaluronic acid 25mg) | Prism Life Sciences | Standard Commercial Pack | — |
| Cartil Forte, [Glucosamine 500mg, Chondroitin Sulphate 200mg, Vit D3 200 i.u, Vit B12 10 mcg, Vit C 30 mg, Vit E 20 mg Folic acid 200 mcg, Zinc 7.5 mg, Manganese, Boron 1.5, Cu, 1 mg, Selenium 100 mcg | Meyer Organics | Standard Commercial Pack | — |
| Cartil Omega (Glucosamine 500mg, Chondroitin 200mg, Sodium hyaluronate 3mg, Omega 3 fish oil provides EPA 60 mg & DHA 40 mg Plus other vitamins & Minerals) | Meyer Organics | Standard Commercial Pack | — |
| Viscoat | Alcon Pharmaceuticals | Standard Commercial Pack | — |
Special populations
Pregnancy & lactation
Pregnancy
Use only if potential benefit justifies potential risk; prefer agents with better reproductive data when alternatives exist.
Lactation
Assess infant risk vs benefit of maternal therapy; prefer agents with lactation data.
Diet
Food & alcohol
- Food
- Food
Trust
Sources & disclaimer
Source: Local active-ingredient clinical extract; Professional class pharmacology (Therapeutic agent (verify pharmacological class))
Last reviewed: 01 Aug 2026
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.