Kenyan Health Patient Information Leaflet
Biguanide antidiabetic
Uncomplicated and non-ketonic diabetes mellitus (maturity onset type II diabetes). Clinical selection for Metformin / Glibenclamide should follow culture results where relevant, Kenya STG/EML recommendations, and the current product SmPC. Class context: Biguanide antidiabetic. Confirm site-specific dose, duration and monitoring before prescribing.
Initial dose: One tablet (5mg /500mg) OD (Max. daily dose: 20mg/2000mg)
[Metformin] Diarrhoea, nausea, abdominal discomfort, metallic taste. Serious: lactic acidosis (rare, high mortality if occurs). [Glibenclamide] GI disturbances; blood dyscrasia; hypoglycaemia; jaundice; skin rashes; hypersensitivity reactions; headache; dizziness; oedema; hyponatraemia; paraesthesia; photosensitivity.
Store as labelled. Keep out of reach of children.